Session # JCO Supplement e13109

Comparing actionable results for breast and colorectal cancer patients across multigene panels.

  • For both breast cancer and colorectal cancer patients, the utilization of a multi-gene panel with more genes led to more positive results than a multi-gene panel with fewer genes, and the vast majority of additional findings occur in genes with published management guidelines.
  • These additional positive results can impact treatment decisions and cancer risk management, including earlier and/or more frequent screening,chemoprevention, and/or other measures.
  • In some cases, positive results occurred in genes not associated with the patient’s cancer diagnosis, but may still impact risk management for other cancer(s).

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