Session # P-005

An update on APC p.I1307K homozygosity: Observations from 74 individuals from a large multigene panel testing cohort

Presenting Author: Dr. Aimee Lucas, MD from Icahn School of Medicine at Mount Sinai

Take home point: 

• APC p.I1307K homozygotes are not at appreciably increased risk for colon cancer or polyps relative to APC p.I1307K heterozygotes in a clinical genetic testing laboratory cohort.

• Authors: Marcy E. Richardson; Taylor D. Coleman; Carrie Horton; Magan Trottier; Linda Polfus​; Leah Zaretsky; Maggie Feng; Aimee Lucas
• Collaborators: Icahn School of Medicine at Mount Sinai; WCG Clinical Inc.
• Conference: CGA-IGC 2025
• Date: Thursday, Oct 09, 2025 6:00pm - 7:00pm