Oncology

Session # 127

Phenotype and Colorectal Cancer Risk in APC I1307K Homozygotes.

  • This is the largest cohort of APC I1307K homozygotes reported to date.
  • APC I1307K homozygotes do not appear to have an increased risk for polyposis or other features associated with classic FAP, although one had a desmoid tumor.
  • Similar to heterozygotes, homozygotes appear to have an increased risk for colorectal cancer.

  • Authors: Kory Jasperson; Mary Pritlzaff
  • Conference: Collaborative Group of the Americas on Inherited Colorectal Cancer (CGA-ICC)
  • Date: Friday, Oct 20, 2017 5:30pm - 7:00pm

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