Session # 621F

Role of HOXB13 in breast and ovarian cancer: Preliminary data from a laboratory-based multigene panel testing cohort.

  • HOXB13 p.G84E was more common in probands with prostate cancer compared the general population.
  • HOXB13 p.G84E was not more common in probands with breast or ovarian cancer compared to the general population.
  • These results reinforce the association between HOXB13 and prostate cancer; however, more data is needed to determine if female carriers are at increased risk to develop cancer.

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