EducateNext: DNA Methylation Episignatures as Diagnostic Biomarkers for Rare Disease with Bekim Sadikovic, PhD, DABMG, FACMG

• This webinar will explore the role of DNA methylation episignatures as clinically actionable biomarkers for the diagnosis of rare genetic disorders. Dr. Bekim Sadikovic will highlight how genome-wide methylation profiling enables functional interpretation of genetic variation, including the resolution of variants of uncertain significance, while also supporting screening in patients with suspected genetic disease. The session will provide insight into the development, validation, and global implementation of episignature-based testing in clinical laboratories. Emphasis will be placed on real-world applications, demonstrating how epigenomic data can improve diagnostic yield and advance precision medicine.

  Level of Instruction: Intermediate

   

  *** Continuing Education Credit Information ***  
   
  - Only the live session qualifies for CEUs. You must join through the link; if you call-in only your name will not appear on the attendance report.  
   
  - Certified GCs: NSGC 0.1 CEU/one Category 1 contact hour per webinar is awarded at the end of the series (in December through the NSGC portal, not by email). You must create a NSCG account (www.nsgc.org).  
   
  - Laboratory Personnel: P.A.C.E. certificate is 1 PACE unit/contact hour is awarded per webinar. PACE certificate is available 1-week post-session (through the ASCLS CE Organizer)

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  Ambry Genetics is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E. ® Program.

  

  Only the live session qualifies for CEUs but when possible, we host the recordings on our website and NSGC recommends participants to use their personal email instead of work email addresses to ensure they receive their CEU certificates.

  

  Ambry Genetics is approved as a provider for continuing education program by NSGC and ASCLS P.A.C.E ® Program.

Bekim Sadikovic, PhD, DABMG, FACMG | Presenter

Professor, Research Chair, CSO

Dr. Bekim Sadikovic is the Research Chair in Clinical Genomics and Epigenomics at London Health Sciences Centre and Professor at Western University. He serves as Division Head of Molecular Diagnostics and Scientific and Clinical Director of the Verspeeten Clinical Genome Centre. Dr. Sadikovic is a pioneer in the development and clinical implementation of DNA methylation episignatures, leading the creation of EpiSign, a globally adopted platform for the diagnosis of rare genetic disorders. His work focuses on translating epigenomic discoveries into scalable clinical tools that improve diagnostic yield and enable precision medicine. He is also Founder and Chief Scientific Officer of EpiSign Inc., advancing innovation at the intersection of genomics, epigenomics, and AI.

Caitlin Reid, MS, LGC, CGC | Moderator

Genomic Science Liaison, Ambry Genetics

Caitlin joined Ambry Genetics in 2021 as the Oncology Genomic Science Liaison for the Midwest territory. In her current role, she serves as a clinical liaison for the field team to educate health care providers and key opinion leaders on genetic testing and genomic medicine. Caitlin previously worked as an Oncology Genetic Counselor at the University of Iowa in the Holden Comprehensive Cancer center. Caitlin received her Bachelor of Science degree in Biology with a concentration in cell and developmental biology from the University of Iowa. She earned her Master of Science degree in Genetic Counseling from the University of Michigan in 2018 and is certified by the American Board of Genetic Counseling.