TXNDC3

Aliases 
NME8; CILD6; SPTRX2; NM23-H8; sptrx-2
Chromosomal Locations 
7p14.1

 

This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive.
 
The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.[provided by RefSeq, Nov 2009]

 

Description 
thioredoxin domain-containing protein 3; sperm-specific thioredoxin 2; spermatid-specific thioredoxin-2
Tests 
Primary Ciliary Dyskinesia Next-Gen Sequencing Panel (includes CFTR)