Session # 211

Molecular diagnosis for neurodevelopmental disorders-an overview of multi-gene panels and whole exome sequencing

• MGP are useful to provide low cost, quick testing that avoids incidental findings.
• Comprehensive array and MLPA tests included in MGP help to detected gross indels in targeted genes.
• DES testing has the advantage of routinely identifying de novo alterations, novel genetic etiologies and classifying VUS by segregation information.
• MGP that include parental testing for co-segregation analysis can help to improve the diagnostic yield and reduce

• Authors: Jing Wang; Zöe Powis; Amal Yussuf; Jade Tinker; Heather Newman; Tiffiney Carter; Erica Smith; Rhonda Lassiter; Shoji Ichikawa; Negar Ghahramani; Sherry Dadgar; Brigette Tippin Davis; Amanda Bergner
• Conference: AAN 2017
• Date: Tuesday, Apr 25, 2017 5:30pm - 7:00pm