The field of precision medicine is rapidly growing. New biomarkers and therapies are continuously being identified, constantly changing the field of precision oncology, and challenging providers to stay up-to-date with the latest biomarker testing. This session will focus on the advancements in somatic tumor testing, from conventional biomarker assays to multi-omic techniques. Today, comprehensive somatic molecular profiling offers a cutting-edge approach that provides oncology care teams essential information to guide personalized clinical management and identify therapeutic options to most effectively treat a patient’s cancer.