Misattributed Parentage as an Unanticipated Finding during Clinical Genomic Sequencing with Josh Deignan, PhD, FACMG, CGMB, MB(ASCP)CM

  • [Recording unavailable]

    Clinical laboratories performing exome or genome sequencing are familiar with the challenges associated with proper consenting for and reporting of medically actionable secondary findings based on recommendations from the American College of Medical Genetics and Genomics (ACMG). Misattributed parentage is another type of unanticipated finding a laboratory may encounter during family-based exome or genome sequencing; however, there are currently no professional recommendations related to the proper consenting for and reporting of misattributed parentage encountered during exome or genome sequencing.  This presentation will provide an overview of the various challenges associated with the detection and communication of unanticipated misattributed parentage.

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    Ambry Genetics is approved as a provider for continuing education program by NSGC and ASCLS P.A.C.E ® Program.


Josh Deignan, PhD, FACMG, is an Associate Clinical Professor in the Department of Pathology and Laboratory Medicine in the David Geffen School of Medicine at UCLA. He is one of the Associate Directors of the UCLA Molecular Diagnostics Laboratories, specializing in the areas of molecular genetics and genomics. He performed his undergraduate work in Genetics at the University of California, Davis, and he received his Ph.D. in Pathology and completed his medical genetics fellowship training at UCLA. He is board-certified by the American Board of Medical Genetics and Genomics in Clinical Molecular Genetics and Genomics and is licensed by the state of California as a Clinical Genetic Molecular Biologist (CGMB). 


Selvi Palaniappan is a certified genetic counselor and Oncology Genetic Specialist at Ambry Genetics. Prior to gaining her M.S. in Genetic Counseling from University of California, Irvine, Selvi was a researcher at the Howard Hughes Medical Institute at University of Michigan. She joined Ambry after more than 20 years of working clinically at Emory University, Vanderbilt Ingram Cancer Center, and most recently, developing a cancer genetics program at Northside Hospital in Atlanta, Georgia.

  • Fri, November 15, 2019
  • 12:00pm PST
  • Duration: 1 hour
  • C.E.U.
    1 Category 1 Contact Hour
  • P.A.C.E. 1 unit

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