Ionis Pharmaceuticals, Inc., and Ambry Genetics are partnering to offer no-cost, confidential genetic testing and confidential genetic counseling to patients through the hATTR Compass Genetic Testing Program who are clinically suspected of having hereditary ATTR amyloidosis with polyneuropathy as well as individuals with a family history of hereditary ATTR amyloidosis.
The hATTR Compass Program is available for patients 18 years and older who have symptoms consistent with hereditary ATTR amyloidosis with polyneuropathy as well as individuals who have a family history of hereditary ATTR amyloidosis.
hATTR Compass is a no-cost genetic testing program operated through Ionis Pharmaceuticals and Ambry Genetics. Ambry Genetics does not share any patient identifiable information.
The hATTR Compass Genetic Testing Program is designed to:
- Help accelerate or confirm the diagnosis of hereditary ATTR amyloidosis with polyneuropathy
- Provide support and resources to patients, caregivers and healthcare professionals throughout the genetic testing process
- Empower patients and their healthcare professionals to make the most informed decisions about their health care
Who is eligible?
The hATTR Compass Program is available for patients 18 years and older who have symptoms consistent with hereditary ATTR amyloidosis with polyneuropathy as well as individuals who have a family history of hereditary ATTR amyloidosis.
What test is right for your patient?
Single-gene test for TTR Select this test to confirm suspected diagnosis
92-gene panel targeting patients with who have mixed phenotypes, including hereditary ATTR amyloidosis Select this test for a comprehensive genetic assessment of patients with a mixed phenotype.
81-gene panel targeting patients with hereditary neuropathies, including hereditary ATTR amyloidosis. Select this test for a comprehensive genetic assessment of your neuropathy patients.
Sponsored genetic counseling
Genetic counselors are available at no cost to consult with your patient through pre-test and post-test counseling. Genetic counselors from a third-party genetic counseling service working with the hATTR Compass Program, are trained to help patients navigate the social and emotional aspects of genetic testing. During pre-test counseling, a genetic counselor will be available by phone to discuss the benefits, limitations and implications of genetic testing with your patient. During post-test genetic counseling, a genetic counselor will be available by phone to help your patient interpret their results and the potential implications for them and their families. If requested, genetic counselors can review treatment options available and provide additional resources. If your patient is interested in this confidential service, make sure to indicate in the ordering form if your patient would like to have pre-test and/or post-test counseling. If indicated, a customer service representative will contact your patient to schedule the designated counseling session(s).
What is genetic counseling?
How do I enroll my patient?
- Order a Sample Kit: Click on Order a Sample Kit button on the right. A custom ordering form will ship with each kit.
- Collect Samples: Use the hATTR Compass Genetic Testing Kit provided to you by mail or Ambry representative to collect your patient’s blood or saliva DNA samples. Complete the Test Requisition Form provided with the kit. Tip: Be sure to indicate whether your patient would like to receive confidential genetic counseling on the order form.
- Submit for DNA Analysis: Submit the hATTR Compass Kit for DNA analysis with the completed Test Requisition Form using the mailing instructions provided in your kit.
- Receive Results: Your patient’s results will be sent to you within 2-4 weeks. Tip: Ambry Genetic Counselors are available to help you interpret the test results. For assistance, contact +1 949-900-5500.
- Make a Plan: Work with your patient to make a healthcare management plan based on their test results. Tip: If you’d like to learn more about hereditary ATTR amyloidosis, start here www.hATTRGuide.com.
We’re here to help you every step of the way. If you have any questions about the hATTR Compass Program, contact us at +1 949-900-5500.
The hATTR Compass Program is currently available in the United States, Canada and Puerto Rico. While Ionis Pharmaceuticals provides financial support for this program, all tests and services are confidential and performed by independent third parties.
At no time does Ionis Pharmaceuticals receive patient identifiable information.
How to order a test
Submit a paper Test Request Form (TRF)
AmbryPort® (online ordering portal)
Login
or
create an account
- Download custom TRF above
- Complete TRF
- Collect patient DNA sample (blood or saliva)*
- Ship the Sample Submission Kit, with the completed TRF, using the pre-paid FedEx envelope
- Receive your secured report through AmbryPort, fax or e-mail
* You can also send a saliva kit directly to your patient’s home for them to submit their saliva sample. Just check the “Sent kit to patient” box in the TRF. We will ship a kit to your patient as soon as we receive your TRF.
Sign up on AmbryPort and start an order by adding a new patient
Click here
Enter the partner code
"hATTR"
in the Partner Code box on the patient information section
Select appropriate test for your patient. Don’t forget to check pre- and/or post-test genetic counseling
Complete all required fields and authorize eTRF using DocuSign
We’re here to help you every step of the way. If you have any questions about the hATTR Compass Program, contact us at +1 949-900-5500.