Microsatellite instability (MSI) analysis

Microsatellite instability (MSI) testing analyzes colon, endometrial, and other tumor tissue samples. It can be used to screen tumors for mismatch repair deficiency (MMRd), and to find individuals who may be at-risk for Lynch syndrome. The results of MSI testing can guide the next steps for your patient with regards to treatment recommendations, as well as further testing for Lynch syndrome.

Quick Reference
Test Code 8702
Turnaround Time (TAT) 3-4 weeks
Number of Genes 0

Ordering Options

We now offer single site analysis (SSA) at no additional cost to family members

following single gene or panel testing* of the first family member (proband) within 90 days of the original Ambry report date.

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*excludes Exome and SNP Array tests

Why Is This Important?

Key Benefits of MSI Testing:

  1. Identify patients with MMRd who may benefit from treatment with PD-L1/PD-1 immunotherapy drugs
  2. Identify patients who may be at-risk for Lynch syndrome 
  3. May help determine other treatment recommendations for colorectal cancer
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