Oncology

Session # A-112

Gene Characterization: A scientific approach to multi-gene panel testing design.

  • When designing MGPTs, a proper gene vetting process may improve detection rates
  • Rates of clinically significant findings of MGPTs tend to increase with inclusion of genes with higher clinical validity scores
  • VUS rates of MGPTs tend to increase with inclusion of genes with limited clinical validity without increasing the mutation rate

  • Authors: Bess Wayburn; Tricia Zion; Sourat Darabi; Devon Lamb Thrush; Erica Smith; Tami Johnston; Brissa Martin; Kelly Farwell Hagman; Melissa Para; Brigette Tippin Davis
  • Conference: National Society of Genetic Counselors (NSGC)
  • Date: Wednesday, Sep 13, 2017 5:15pm - 6:30pm

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