ATP7B

Aliases 
PWD, WC1, WD, WND
Chromosomal Locations 
13q14.3

This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites.

This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been associated with Wilson disease (WD).

Description 
ATPase, Cu++ transporting, beta polypeptide ATPase, Cu(2+)- transporting, beta polypeptide Wilson disease-associated protein copper pump 2 copper-transporting ATPase 2
Tests