Evaluating Zebrafish Assays

  • Zebrafish (Danio rerio) are an emerging genetic model system for biomedical research. We will discuss the usefulness of zebrafish in studying genetics and development including ability to visualize early developmental processes and the ease of both forward and reverse genetic techniques. Due to a high level of genetic homology of the vertebrate species, zebrafish are well-suited for studying many disease-relevant genes and diseases that affect many organ systems including brain, heart, muscle, craniofacial and axial skeleton. While there are many benefits for using zebrafish to study human genetic disease, there are limitations, including artifacts of genetic manipulation that can be misinterpreted. In order to critically evaluate published literature, it is necessary to understand that small heads with small eyes, overall necrotic cells, cardiac-edema, and bent tails may not be specific to the gene targeted. Proper experimental design is crucial for understanding the role of a particular gene or variant in genetics and development.

    Please note: You must attend the full length of the live course and complete the evaluation in order to claim CEUs.

  • Mon, August 7, 2017
  • 12:00pm PDT
  • Duration: 1 hour
  • C.E.U. 1 unit
  • P.A.C.E. 1 unit

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